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Can RSO Hurt Your Stomach? – (Know The Causes & Cure)

Are you considering using RSO (Rick Simpson Oil) for its acclaimed therapeutic benefits but are concerned about potential stomach discomfort? 

You’re not alone. Many people share your concern, wondering: Can RSO hurt your stomach

Indeed, RSO can potentially cause stomach discomfort, mainly due to its high potency and the way it interacts with our body’s endocannabinoid system. However, discomfort can often be managed by adjusting the dosage, modifying dietary habits, and consulting with a healthcare provider.

Can RSO Hurt Your Stomach? – Brief Guide

RSO, despite its potential therapeutic benefits, can occasionally lead to stomach discomfort in some users. 

The cause of this discomfort usually lies in the high THC content of the oil, which interacts with our body’s endocannabinoid system, potentially causing a range of effects. 

These effects can be particularly noticeable in the stomach, where the THC might stimulate gastric acid secretion and disrupt the natural pH balance. 

This disruption can trigger stomach discomfort, especially in individuals with sensitive stomachs or pre-existing conditions. 

However, methods such as adjusting dosage, altering dietary habits, and taking over-the-counter remedies can often mitigate these symptoms. 

Nonetheless, it’s always wise to consult with a healthcare provider if you experience persistent or severe discomfort.

So Can RSO Really Hurt Your Stomach Or Is It A Myth?

RSO, due to its high concentration of THC, can potentially cause stomach discomfort in some individuals. This high potency can result in side effects ranging from mild nausea to more severe gastrointestinal distress. 

It’s worth noting that these reactions vary significantly among individuals, with some experiencing no discomfort at all while others may have more pronounced side effects.

Scientific studies, although limited, have shown that cannabis-related products can have both beneficial and adverse effects on the gastrointestinal system. 

On the one hand, THC, the active component in RSO, has been reported to have anti-inflammatory properties that may be beneficial for certain gastrointestinal conditions. 

Also, some individuals may experience negative effects such as diarrhea, stomach cramps, or nausea.

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Why RSO Might Hurt the Stomach?

Understanding the physiological reasons why RSO might cause stomach discomfort involves delving into its impact on the gastrointestinal system. 

The human body has a complex system of endocannabinoid receptors located throughout various organs and tissues, including the digestive tract. 

When RSO is consumed, the active compound, THC, interacts with these receptors, potentially leading to diverse effects. 

Depending on the individual and the dose, these effects may range from a subtle feeling of discomfort to more pronounced pain.

1. Interaction with Endocannabinoid System

Our bodies naturally produce endocannabinoids, neurotransmitters that bind to cannabinoid receptors in your nervous system. Consuming RSO introduces THC to this system, which then interacts with the cannabinoid receptors, potentially causing a range of effects, including discomfort or pain.

2. Potential Irritation of Stomach Lining

High concentrations of THC could stimulate gastric acid secretion, potentially leading to a disruption of the stomach lining’s natural pH balance. This disruption could cause irritation or discomfort, especially in individuals with sensitive stomachs or pre-existing conditions such as gastritis.

3. Reaction to High THC Concentration

The high concentration of THC in RSO is potent. For some individuals, especially those new to cannabis products or with a low tolerance level, this could potentially result in adverse reactions, including stomach discomfort.

How to Mitigate the Potential Stomach Discomfort Caused by RSO

While there are potential discomforts associated with RSO use, several strategies can be implemented to mitigate these effects. These approaches mainly involve adjusting consumption methods and tweaking lifestyle habits.

1. Adjust Dosage

Starting with a lower dosage of RSO allows the body to gradually adjust to the new substance, reducing the likelihood of discomfort. As the saying goes, “start low and go slow.” This approach gives your body a chance to adapt and respond, allowing you to gauge your body’s reactions more accurately.

2. Modify Dietary Habits

Consuming RSO with food, particularly foods high in healthy fats like avocados or nuts, can help to buffer the stomach and slow the absorption of THC, potentially reducing discomfort. It’s also advisable to stay hydrated and avoid alcohol, which can exacerbate stomach irritation.

3. Take Breaks

If you’re using RSO regularly and experience discomfort, it might be helpful to take short breaks. This approach allows your body to recover and can help in identifying whether RSO is the actual cause of the discomfort.

How to Cure Stomach Pain Caused by RSO

In the event that you experience stomach discomfort after using RSO, there are a few potential treatments you can consider. Over-the-counter remedies and lifestyle changes may provide relief, but it’s crucial to consult with a healthcare provider if the discomfort persists or is severe.

  1. Over-The-Counter Remedies: Antacids or acid reducers may provide temporary relief by neutralizing the stomach acid and reducing inflammation.
  2. Dietary Adjustments: Consuming a bland diet, rich in foods that are easy on the stomach, like bananas, rice, applesauce, and toast, can help alleviate discomfort. Additionally, increasing fiber intake can improve overall gut health and potentially reduce discomfort.
  3. Lifestyle Changes: Managing stress through mindfulness techniques such as yoga or meditation and maintaining regular sleep patterns can also help to improve overall gut health, potentially reducing the frequency and intensity of discomfort.
  4. Consult a Healthcare Provider: If your discomfort is persistent or severe, seek advice from a healthcare provider. They may suggest further investigations to determine the cause and recommend treatments accordingly.

Always remember that while these treatments can provide relief, they are not a ‘one-size-fits-all’ solution; everyone’s body is unique, and what works for one person may not work for another. This reinforces the importance of personalized medical advice.

Case Studies and Anecdotal Evidence

Anecdotal evidence and case studies can provide a more personal perspective on the issue of RSO and stomach discomfort. These real-life stories can offer insights into the range of experiences that individuals may have.

For instance, some people report mild discomfort when starting with RSO, which subsides over time as their bodies adjust. Others have shared that they found relief by adjusting the dosage, changing their dietary habits, or using over-the-counter remedies.

However, it’s crucial to remember that anecdotal evidence and case studies are not a substitute for professional medical advice. Each person’s body is unique, and reactions to substances like RSO can vary widely.


In conclusion, while RSO can potentially cause stomach discomfort, this is generally manageable and varies significantly among individuals. 

Various strategies can mitigate these effects, from adjusting your dosage and dietary habits to implementing lifestyle changes and seeking advice from a healthcare provider. 

However, it’s important to remember that each individual’s response to RSO is unique, and what works for one person may not work for another. 

As with any treatment, a personalized approach under the guidance of a healthcare provider is crucial. Above all, it’s important to listen to your body and make informed decisions about your health.


1. What is RSO and how can it potentially cause stomach discomfort?

RSO (Rick Simpson Oil) is a potent cannabis-derived oil high in THC. It can potentially cause stomach discomfort due to its interaction with the endocannabinoid system and the potential to stimulate gastric acid secretion.

2. How can I mitigate potential stomach discomfort caused by RSO?

Mitigating potential stomach discomfort caused by RSO involves adjusting your dosage, modifying dietary habits to include foods high in healthy fats, staying hydrated, and avoiding irritants like alcohol.

3. Can lifestyle changes help reduce stomach discomfort caused by RSO?

Yes, lifestyle changes such as managing stress, maintaining regular sleep patterns, and increasing fiber intake can improve gut health and potentially reduce discomfort caused by RSO.

4. Should I consult a healthcare provider if I experience severe stomach discomfort from RSO?

Yes. Persistent or severe stomach discomfort after using RSO should warrant a consultation with a healthcare provider for personalized advice and potential treatment options.


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